Identification of cell proliferation-associated epitope on CD98 oncoprotein using phage display random peptide library
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چکیده
منابع مشابه
identification of hitherto undefined b-cell epitopes by antibodies in the sera of vitiligo patients using phage-display peptide library
a random 12 mers phage library was used to screen a pool of immunoglo¬bulin fractions obtained from vitiligo patients. subsequent to panning experiments, a panel of affinity selected phage from vitiligo patients were obtained. this panel was tested using an elis a for their reactivity with pooled sera from patients and normal controls. among the 16 randomly selected clones, two of clones showed...
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Phage display peptide libraries are widely used in various protein-protein interaction studies to determine the immunological binding of proteins and epitope mapping of different targets. In the present study, the peptide library is used to identify the Fab binding epitope site of Tetanus Toxoid (TT). The peptides were screened against Fab by biopanning, using a random peptide 12mer phage displ...
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BACKGROUND The gp90 protein of avian reticuloendotheliosis-associated virus (REV-A) is an important envelope glycoprotein, which is responsible for inducing protective antibody immune responses in animals. B-cell epitopes on the gp90 protein of REV have not been well studied and reported. METHODS AND RESULTS This study describes the identification of a linear B-cell epitope on the gp90 protei...
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The commercial availability of random peptide libraries displayed on the M13 phage is increasing their use forstudies on epitope identification, enzyme inhibitors, receptor ligands, etc. In this study two experimentswhere planned for selection of peptides. First with sheep antibodies, the positive selector was IgG, preparedon Protein G column from a pool of 11 sheeps immunized...
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The Antibody-Dependent Enhancement (ADE) hypothesis has been proposed to explain why more severe manifestations of Dengue Hemorrhagic Fever and Dengue Shock Syndrome (DHF/DSS) occur predominantly during secondary infections of Dengue Virus (DV) with different serotypes. However, the epitopes recognized by these enhancing antibodies are unclear. Recently, antipre-M monoclonal antibody (mAb 70-21...
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ژورنال
عنوان ژورنال: Cancer Science
سال: 2007
ISSN: 1347-9032,1349-7006
DOI: 10.1111/j.1349-7006.2007.00587.x